Autosomal Dominant Polycystic Kidney Disease (ADPKD) Wall of Experts
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Have additional questions? Ask our experts here.
Natural History
How does the genetic profile of ADPKD impact the disease course?
Dr. York Pei
How does the genetic profile of ADPKD impact the disease course?
What is the typical pattern of cyst development and progression in ADPKD?
Dr. Phil McFarlane
What is the typical pattern of cyst development and progression in ADPKD?
What are the risk factors for ADPKD disease progression?
Dr. Neera Dahl
What are the risk factors for ADPKD disease progression?
What is the relationship between growth in kidney volume and kidney function in ADPKD?
Dr. Phil McFarlane
What is the relationship between growth in kidney volume and kidney function in ADPKD?
Should we be screening for intracranial aneurysms in ADPKD patients?
Dr. Navdeep Tangri
Should we be screening for intracranial aneurysms in ADPKD patients?
Diagnosis
How do you diagnose ADPKD and what is the role of genetic testing?
Dr. Ahsan Alam
How do you diagnose ADPKD and what is the role of genetic testing?
What is the role of TKV in practice?
Dr. Neera Dahl
What is the role of TKV in practice?
How should we assess total kidney volume?
Dr. Neera Dahl
How should we assess total kidney volume?
Treatment
What is the evidence supporting the use of water therapy for ADPKD?
Dr. York Pei
What is the evidence supporting the use of water therapy for ADPKD?
What is the presumed mechanism of action of tolvaptan in ADPKD?
Dr. Phil McFarlane
What is the presumed mechanism of action of tolvaptan in ADPKD?
What role can modulation of the RAAS and blood pressure play in the treatment of ADPKD?
Dr. Ahsan Alam
What role can modulation of the RAAS and blood pressure play in the treatment of ADPKD?
What are the data supporting use of Tolvaptan for ADPKD?
Dr. Neera Dahl
What are the data supporting use of Tolvaptan for ADPKD?
What is the status of the evidence for the use of mTOR inhibitors for ADPKD?
Dr. Paul Tam
What is the status of the evidence for the use of mTOR inhibitors for ADPKD?
How is tolvaptan dosed and titrated?
Dr. Philip McFarlane
How is tolvaptan dosed and titrated?
What potential drug interactions should we be aware of with tolvaptan?
Dr. Paul Tam
What potential drug interactions should we be aware of with tolvaptan?
What is the tolvaptan Hepatic Safety and Monitoring Programme (HSMP)?
Dr. Navdeep Tangri
What is the tolvaptan Hepatic Safety and Monitoring Programme (HSMP)?
What is the liver toxicity profile of tolvaptan in ADPKD?
Dr. York Pei
What is the liver toxicity profile of tolvaptan in ADPKD?
What is the presumed mechanism of action of tolvaptan and what is the evidence of efficacy?
Dr. Navdeep Tangri
What is the presumed mechanism of action of tolvaptan and what is the evidence of efficacy?
What happens if you stop tolvaptan therapy?
Dr. Neera Dahl
What happens if you stop tolvaptan therapy?
À la fin de ce programme, les participants seront en mesure :
English
Once you review this material, try this self assessment.
Have additional questions? Ask our experts here.
Natural History
How does the genetic profile of ADPKD impact the disease course?
Dr. York Pei
How does the genetic profile of ADPKD impact the disease course?
What is the typical pattern of cyst development and progression in ADPKD?
Dr. Phil McFarlane
What is the typical pattern of cyst development and progression in ADPKD?
What are the risk factors for ADPKD disease progression?
Dr. Neera Dahl
What are the risk factors for ADPKD disease progression?
What is the relationship between growth in kidney volume and kidney function in ADPKD?
Dr. Phil McFarlane
What is the relationship between growth in kidney volume and kidney function in ADPKD?
Should we be screening for intracranial aneurysms in ADPKD patients?
Dr. Navdeep Tangri
Should we be screening for intracranial aneurysms in ADPKD patients?
Diagnosis
How do you diagnose ADPKD and what is the role of genetic testing?
Dr. Ahsan Alam
How do you diagnose ADPKD and what is the role of genetic testing?
What is the role of TKV in practice?
Dr. Neera Dahl
What is the role of TKV in practice?
How should we assess total kidney volume?
Dr. Neera Dahl
How should we assess total kidney volume?
Treatment
What is the evidence supporting the use of water therapy for ADPKD?
Dr. York Pei
What is the evidence supporting the use of water therapy for ADPKD?
What is the presumed mechanism of action of tolvaptan in ADPKD?
Dr. Phil McFarlane
What is the presumed mechanism of action of tolvaptan in ADPKD?
What role can modulation of the RAAS and blood pressure play in the treatment of ADPKD?
Dr. Ahsan Alam
What role can modulation of the RAAS and blood pressure play in the treatment of ADPKD?
What are the data supporting use of Tolvaptan for ADPKD?
Dr. Neera Dahl
What are the data supporting use of Tolvaptan for ADPKD?
What is the status of the evidence for the use of mTOR inhibitors for ADPKD?
Dr. Paul Tam
What is the status of the evidence for the use of mTOR inhibitors for ADPKD?
How is tolvaptan dosed and titrated?
Dr. Philip McFarlane
How is tolvaptan dosed and titrated?
What potential drug interactions should we be aware of with tolvaptan?
Dr. Paul Tam
What potential drug interactions should we be aware of with tolvaptan?
What is the tolvaptan Hepatic Safety and Monitoring Programme (HSMP)?
Dr. Navdeep Tangri
What is the tolvaptan Hepatic Safety and Monitoring Programme (HSMP)?
What is the liver toxicity profile of tolvaptan in ADPKD?
Dr. York Pei
What is the liver toxicity profile of tolvaptan in ADPKD?
What is the presumed mechanism of action of tolvaptan and what is the evidence of efficacy?
Dr. Navdeep Tangri
What is the presumed mechanism of action of tolvaptan and what is the evidence of efficacy?
What happens if you stop tolvaptan therapy?
Dr. Neera Dahl
What happens if you stop tolvaptan therapy?
